Concept #1: The Spike-Initiating Zone
Concept #2: Longitudinal Currents and AP Spread
Concept #3: Active vs. Passive Spread
Concept #4: The Function of Myelination
Practice: A neuron is depolarized from Vrest= -70 mV to -30 mV in its dendrite. As a result of this depolarization, Vm at the spike-initiating zone remains at Vm= -70 mV. Which of the following is likely to happen in this neuron as a result of this depolarization in the dendrite?
Practice: Multiple sclerosis is a chronic disease characterized by demyelination of neuronal axons. Which of the following accurately describes the predicted effects of multiple sclerosis on neuronal conduction velocity and action potential spread, respectively?