Ch. 14 - Synthetic TechniquesWorksheetSee all chapters
All Chapters
Ch. 1 - A Review of General Chemistry
Ch. 2 - Molecular Representations
Ch. 3 - Acids and Bases
Ch. 4 - Alkanes and Cycloalkanes
Ch. 5 - Chirality
Ch. 6 - Thermodynamics and Kinetics
Ch. 7 - Substitution Reactions
Ch. 8 - Elimination Reactions
Ch. 9 - Alkenes and Alkynes
Ch. 10 - Addition Reactions
Ch. 11 - Radical Reactions
Ch. 12 - Alcohols, Ethers, Epoxides and Thiols
Ch. 13 - Alcohols and Carbonyl Compounds
Ch. 14 - Synthetic Techniques
Ch. 15 - Analytical Techniques: IR, NMR, Mass Spect
Ch. 16 - Conjugated Systems
Ch. 17 - Aromaticity
Ch. 18 - Reactions of Aromatics: EAS and Beyond
Ch. 19 - Aldehydes and Ketones: Nucleophilic Addition
Ch. 20 - Carboxylic Acid Derivatives: NAS
Ch. 21 - Enolate Chemistry: Reactions at the Alpha-Carbon
Ch. 22 - Condensation Chemistry
Ch. 23 - Amines
Ch. 24 - Carbohydrates
Ch. 25 - Phenols
Ch. 26 - Amino Acids, Peptides, and Proteins
Synthetic Cheatsheet
Moving Functionality
Alkynide Alkylation
Alkane Halogenation

The idea here is that we will be given a target molecule and the reactant and have to work backwards to fill in the missing pieces. 


Let's get started!

Concept #1: Intro


Alright guys these next few questions are cumulative retro synthesis based on the past few chapters of reactions so you do need to still know those and I have made them so that they do represent common types of synthesis, OK? But I've also made them all little bit harder than what I've seen on most tests, OK? That's a good thing what that means is that I'm giving you some hard stuff so that by the time you get to your exam it doesn't feel that bad, OK? You're like "Oh Wow I did harder things with clutch, I did harder things with Johnny online", OK? For all for all these retro syntheses this is that I give you the synthetic cheat sheet is very hopeful so you should be looking at it or referencing it when you're stuck think OK What....Are there any clues here? Are there any ways that I can get unstuck that I can figure out where we're going, OK? So for all of these I would really encourage you to try to do it in your own as best as you can they're all doable none of them are impossible but they are tricky they are hard but they're doable and then of course I'll answer it as always so best of luck guys let's go ahead and get started.

As mentioned in the above video, some of these transformations may be harder than you need to know. Also, know that there are multiple ways to achieve one product but it is important to find the most effective and shortest way possible


Time to put those skills to the test :)

Practice: Supply the reagents necessary to accomplish the following transformation.

Practice: Propose a synthesis

Practice: Supply the reagents necessary to accomplish the following transformation.