Problem: In each reaction box, place the best reagent and conditions from the list below

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We're being asked to determine the best reagents and condition for the given reaction.



Notice that we went from a 2-carbon alkyne to a 5-carbon carboxylic acid.


Step 1: Recall that alkynides can be formed via deprotonation of terminal alkynes. Alkynides react with 0˚ and 1˚ halides via an SN2 reaction to elongate a carbon chain.



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Problem Details

In each reaction box, place the best reagent and conditions from the list below