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We’re being asked to rank the reaction rates of each compound for an SN2 reaction.
Recall that the SN2 reaction follows a backside attack from the nucleophile:
Steric interactions from additional R-groups makes it harder for the nucleophile to attack. This means a more substituted alkyl halide will have a slower reaction rate.
The relative rates for an SN2 reaction are: methyl (fastest) > 1˚ > 2˚ > 3˚ (slowest or no reaction)
Rank the SN2 reaction rates for the following compounds:
2-bromo-3-methylbutane, bromomethane, 1-bromo-3-methylbutane, 2-bromo-2-methylbutane
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Our tutors have indicated that to solve this problem you will need to apply the SN2 Reaction concept. You can view video lessons to learn SN2 Reaction. Or if you need more SN2 Reaction practice, you can also practice SN2 Reaction practice problems.
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Based on our data, we think this problem is relevant for Professor Feducia's class at NCSU.