Problem: The 3 stereocenters in penicillin V, a broad spectrum antibiotic, are labeled “a,” “b,” and “c” in the structure shown below. In each part of this question, the four bonds to the stereocenter are reproduced in the same orientation as they are written in this structure. Assign priorites to each of the four groups attached to the stereocenter (1 = highest priority; 4 = lowest priority), and write the number associated with each group in the appropriate circle. Then, determine whether the absolute stereochemical configuration is (R) or (S). θ

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The 3 stereocenters in penicillin V, a broad spectrum antibiotic, are labeled “a,” “b,” and “c” in the structure shown below. In each part of this question, the four bonds to the stereocenter are reproduced in the same orientation as they are written in this structure. Assign priorites to each of the four groups attached to the stereocenter (1 = highest priority; 4 = lowest priority), and write the number associated with each group in the appropriate circle. Then, determine whether the absolute stereochemical configuration is (R) or (S).

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Our tutors have indicated that to solve this problem you will need to apply the R and S Configuration concept. You can view video lessons to learn R and S Configuration. Or if you need more R and S Configuration practice, you can also practice R and S Configuration practice problems.

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Based on our data, we think this problem is relevant for Professor Daoudi's class at UCF.