Alkynide Retrosynthesis
See all sections| Sections | |||
|---|---|---|---|
| Alkene Stability | 7 mins | 0 completed | Learn Summary |
| Zaitsev Rule | 25 mins | 0 completed | Learn Summary |
| Dehydrohalogenation | 8 mins | 0 completed | Learn |
| Double Elimination | 9 mins | 0 completed | Learn |
| Acetylide | 15 mins | 0 completed | Learn |
| Hydrogenation of Alkynes | 17 mins | 0 completed | Learn Summary |
| Dehydration Reaction | 27 mins | 0 completed | Learn Summary |
| POCl3 Dehydration | 6 mins | 0 completed | Learn |
| Alkynide Synthesis | 16 mins | 0 completed | Learn Summary |
| Additional Practice |
|---|
| Hofmann Elimination of Alkyl Fluorides |
| Debromination |
| Isomerization of Alkynes |
| Dissolving Metal Reduction Mechanism |
| Hydrogenation Retrosynthesis |
| Alkynide Retrosynthesis |
| Bredt's Rule |
Solution: A number of drugs are prepared by reactions in which carbon-carbon bond formation is the last step. Indicate what you believe would be a reasonable last step in the synthesis of the following:
Problem
A number of drugs are prepared by reactions in which carbon-carbon bond formation is the last step. Indicate what you believe would be a reasonable last step in the synthesis of the following:
Practice Problems
Prepare the compound shown below from acetylene.
...
Draw the starting material that, under the given r...
Show how the starting material can be converted to...
The hydrogen on a terminal alkyne carbon is acidic...
A number of drugs are prepared by reactions in whi...
Provide the reagents needed to accomplish each ste...
You need to show how the starting material can be ...
What reagents could be used to accomplish the synt...
Propose a mechanism for the following reaction. In...
Draw the structures of compounds A to D:
Provide the reagent or starting material to perfor...
Synthesize compound A using compounds 1-3 as the o...
Provide a synthetic pathway:What is the starting material that affords the fol...What reagents can be used to form the alkyne produ...Draw an alkyl iodide that could be used to make th...Working backwards, deduce the starting material th...In each reaction box, place the best reagent and c...What acetylide anion and alkyl chloride can be use...