Problem: Relative polarities of the components analgesic drugs: Ibuprofen, acetaminophen, caffeine, salicylamide, acetylsalicylic acid, on their functional groups. What is the behavior of components on the TLC plates based on structure polarity?

FREE Expert Solution

Relative polarity of a compound → depends on their functional groups and affected by the following factors:

  1. hydrogen bond
  2. number of electronegative atoms
  3. polarizability of the bonds or atoms
  4. net dipole moment of the molecule
  5. presence of hetero atoms like oxygen, nitrogen, sulfur

double salts are more polar and methyl is least polar.

  • least polar compound moves the farthest on the TLC plate
    • behavior on TLC plate depends on its structure 
View Complete Written Solution
Problem Details

Relative polarities of the components analgesic drugs: Ibuprofen, acetaminophen, caffeine, salicylamide, acetylsalicylic acid, on their functional groups. What is the behavior of components on the TLC plates based on structure polarity?

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Functional Groups concept. You can view video lessons to learn Functional Groups. Or if you need more Functional Groups practice, you can also practice Functional Groups practice problems.