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Crude extracts from the ginkgo tree, Ginkgo biloba, have been used for centuries to alleviate symptoms associated with asthma. There are four principal components of Ginkgo extracts, called ginkgolide A, B, D, and M. During E. J. Corey’s classic synthesis of ginkgolide B, compound 1 was converted into compound 5 (J. Am. Chem. Soc. 1988, 110, 649–651):
(c) Upon treatment with 4, anion 3 is converted into compound 5, and byproduct 6 is formed. Describe the factors that render 6 a particularly stable anion.
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Our data indicates that this problem or a close variation was asked in Organic Chemistry - Klein 2nd Edition. You can also practice Organic Chemistry - Klein 2nd Edition practice problems.