Problem: For the substituted cyclohexane compound given below, highlight the groups - by clicking on atoms - that will sterically interact with the methyl group in a 1,3-diaxial fashion.

🤓 Based on our data, we think this question is relevant for Professor Goldman's class at UW-SEATTLE.

FREE Expert Solution

We are asked to highlight the groups that will sterically interact with the methyl group in a 1,3-diaxial fashion.


Diaxial interaction (1,3-diaxial interaction) is an interaction between two axial substituents on a cyclohexane ring.

  • This occurs on axial groups that are on the same side of the ring. 

Recall that:

axial groups = energy or stability

equatorial groups = energy or stability


1,3 means that position 1 (Carbon 1 on the ring) is our target group (methyl, CH3) and the other axial group would be on position 3 (carbon 3 on the ring). 


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Problem Details

For the substituted cyclohexane compound given below, highlight the groups - by clicking on atoms - that will sterically interact with the methyl group in a 1,3-diaxial fashion.

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Based on our data, we think this problem is relevant for Professor Goldman's class at UW-SEATTLE.