Problem: 1) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.e. CH3CNf. -OCH3g. NH3h. Br-i. HBrj. CH3OHk. -CNl. nonePart A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")Part B) Which letter corresponds to the leaving group?Part C) Which letter designates the nucleophile?2) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.e. K+f. -OC(CH3)3 g. I-h. CH3OHi. HIj. -OHk. HOC(CH3)3 l. none Part A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")Part B)Which letter corresponds to the leaving group?Part C)Which letter designates the nucleophile?3) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.f. -NH2g. HIh. NH3i. CH3NH2j. I-k. none Part A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")Part B) Which letter corresponds to the leaving group?Part C) Which letter designates the nucleophile?

🤓 Based on our data, we think this question is relevant for Professor Zibuck's class at WAYNE.

FREE Expert Solution

For this problem, we have to determine which among the given reaction is the electrophilic C, leaving group and nucleophile:

  • Recall that the nucleophilic substitution occurs when a nucleophile reacts with an electrophile that does not have an empty orbital or without an acidic hydrogen.
  • A covalent bond MUST be broken to preserve the octet of the electrophile. The bond that is broken to allow this reaction to take place makes a leaving group
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Problem Details

1) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.

e. CH3CN

f. -OCH3

g. NH3

h. Br-

i. HBr

j. CH3OH

k. -CN

l. none

Part A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")

Part B) Which letter corresponds to the leaving group?

Part C) Which letter designates the nucleophile?

2) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.

e. K+

f. -OC(CH3)

g. I-

h. CH3OH

i. HI

j. -OH

k. HOC(CH3)

l. none 

Part A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")

Part B)Which letter corresponds to the leaving group?

Part C)Which letter designates the nucleophile?

3) The two reactants shown below are combined to bring about a nucleophilic substitution reaction.

f. -NH2

g. HI

h. NH3

i. CH3NH2

j. I-

k. none 


Part A) Which letter designates the electrophilic carbon at which substitution occurs? (If no reaction occurs enter the letter corresponding to "none.")

Part B) Which letter corresponds to the leaving group?

Part C) Which letter designates the nucleophile?

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Nucleophilic Substitution concept. You can view video lessons to learn Nucleophilic Substitution. Or if you need more Nucleophilic Substitution practice, you can also practice Nucleophilic Substitution practice problems.

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Our tutors rated the difficulty of1) The two reactants shown below are combined to bring about...as medium difficulty.

What professor is this problem relevant for?

Based on our data, we think this problem is relevant for Professor Zibuck's class at WAYNE.