Organic Chemistry Practice Problems SN2 Reaction Practice Problems Solution: For the following SN2 reaction, draw the organic a...

Solution: For the following SN2 reaction, draw the organic and inorganic products of the reaction, and identify the nucleophile, substrate, and leaving group.

Problem

For the following SN2 reaction, draw the organic and inorganic products of the reaction, and identify the nucleophile, substrate, and leaving group.

Solution

We’re being asked to draw the organic and inorganic products of the given SN2 reaction.



Recall that the SN2 reaction follows a backside attack from the nucleophile:



Because of the backside attack, the SN2 reaction results in the inversion of configuration for chiral centers.


In an SN2 reaction, we have:

nucleophile: a negatively-charged species or a molecule with a lone pair (Lewis base)

• substrate: the molecule that is attacked by the nucleophile

• leaving group: the group that is removed from the substrate and replaced by the nucleophile


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