Adding a single group to a benzene ring is the first step. Now, what happens if we want to do a second reaction on that benzene. Where is it going to add? This is the question we will be answering.
Concept #1: Activity and Directing Effects
Concept #2: Badass Activity Chart
Practice: Predict the major product of the following EAS reaction.
Practice: Predict the product of the following multi-step synthesis.