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We're being asked to determine the **mass percent of ****oxygen** in vancomycin, with the molecular formula C_{66}H_{75}Cl_{2}N_{9}O_{24}.

First, we need to determine the molar mass of vancomycin. We can do this by multiplying the atomic mass of each element with their corresponding number in the molecular formula:

Calculate the percentage by mass of oxygen in the following compounds.

vancomycin, C_{66}H_{75}Cl_{2}N_{9}O_{24}

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