Problem: The binding of oxygen by hemoglobin in the blood involves the following equilibrium reaction: HbH+(aq) + O2(aq) ⇌ HbO2(aq) + H+(aq)In this equation, Hb is hemoglobin. The pH of normal human blood is highly controlled within a range of 7.35 to 7.45. Given the above equilibrium, why is this important? What would happen to the oxygen-carrying capacity of hemoglobin if blood became too acidic (a condition known as acidosis)?

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The binding of oxygen by hemoglobin in the blood involves the following equilibrium reaction: HbH+(aq) + O2(aq) ⇌ HbO2(aq) + H+(aq)

In this equation, Hb is hemoglobin. The pH of normal human blood is highly controlled within a range of 7.35 to 7.45. Given the above equilibrium, why is this important? What would happen to the oxygen-carrying capacity of hemoglobin if blood became too acidic (a condition known as acidosis)?

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