Problem: Color-blindness is an X-linked recessive disorder. Mike is color-blind. His wife, Meg, is homozygous for the normal color vision allele. Using Punnet squares, derive and compare the genotypic and phenotypic ratios expected for the offspring of this marriage.If they have eight children, how many of them would you expect to be color-blind?

🤓 Based on our data, we think this question is relevant for Professor Carr's class at VCU.

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Being an X-linked trait, the genes determining color-blindness is carried by the X chromosomes. Since it is a recessive trait, all the X chromosomes of an individual should have the recessive allele before being expressed. Thus, females would need two copies of the allele as they have two X chromosomes. Males, however, would only need one as their sex chromosomes are made up of one X and one Y chromosome.

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Problem Details

Color-blindness is an X-linked recessive disorder. Mike is color-blind. His wife, Meg, is homozygous for the normal color vision allele. Using Punnet squares, derive and compare the genotypic and phenotypic ratios expected for the offspring of this marriage.

If they have eight children, how many of them would you expect to be color-blind?

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Chromosomal Theory of Inheritance concept. You can view video lessons to learn Chromosomal Theory of Inheritance. Or if you need more Chromosomal Theory of Inheritance practice, you can also practice Chromosomal Theory of Inheritance practice problems.

What professor is this problem relevant for?

Based on our data, we think this problem is relevant for Professor Carr's class at VCU.