Acetylcholine is vital for many functions, including muscle stimulation and memory formation. There are two general mechanisms for its signaling pathway: one is excitatory, such as its induction to produce EPSP; the other is inhibitory, such as the reduction of the heart's pumping rate.
The effects of acetylcholine can be either excitatory or inhibitory. The effect depends on
A. The type of calcium channels in the presynaptic neuron.
B. The type of acetylcholine-activated channel in the post-synaptic membrane.
C. The presence or absence of acetylcholinesterase in the synaptic cleft.
D. whether the presynaptic cell is excitatory or inhibitory.
E. whether calcium flows through the acetylcholine-activated channel.
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