Problem: The following pedigree depicts the inheritance of a hereditary disease affecting the heart. What is the most likely mode of inheritance of this disease? Pay particular attention to individuals 10 & 11.A. autosomal dominantB. autosomal recessiveC. X-linked recessiveD. Y-linkedE. X-linked dominant

FREE Expert Solution

For better understanding of this problem, we'll try to discuss how each wrong answer cannot be correct.

We will eliminate the least likely first.

This is definitely not Y-linked since it can be seen to skip most of the sons of affected fathers.

This is also not autosomal dominant. This can be proven by the progeny of 1 & 2 as it has shown to skip a generation.

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Problem Details

The following pedigree depicts the inheritance of a hereditary disease affecting the heart. What is the most likely mode of inheritance of this disease? Pay particular attention to individuals 10 & 11.

A. autosomal dominant

B. autosomal recessive

C. X-linked recessive

D. Y-linked

E. X-linked dominant

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Chromosomal Theory of Inheritance concept. You can view video lessons to learn Chromosomal Theory of Inheritance. Or if you need more Chromosomal Theory of Inheritance practice, you can also practice Chromosomal Theory of Inheritance practice problems.